The pooled prevalence of impaired cognition during the first year after stroke was 38% ( Sexton et al., 2019). For example, 74 and 41% of the patients reported post-stroke cognitive impairment in median 2 days and 1 year after stroke, respectively ( Horstmann et al., 2014 Sexton et al., 2019). Impaired cognition is another common consequence of stroke ( Sexton et al., 2019), but reported prevalence differs based on time for assessment. Unlike normal tiredness, post-stroke fatigue does not disappear with rest, and, for some patients, the fatigue can become permanent ( Chen and Marsh, 2018). The prevalence of fatigue has been reported to be 50% during the first 2 years after stroke ( Cumming et al., 2016). It has been noted to be one of the most persisting symptoms after stroke ( Broussy et al., 2019) and is linked to crucial deterioration in domains of everyday life (e.g., family, social life, and work life) ( Graber et al., 2019). Post-stroke fatigue has been defined as a subjective feeling of physical and/or mental exhaustion or a constant lack of energy that has a negative impact on quality of life and causes obstacles in the execution of daily chores ( Chen and Marsh, 2018). As a consequence, symptoms that have previously been overlooked, such as fatigue, have been illuminated as having a major impact on an individual’s subjective quality of life ( Graber et al., 2019). The advances in stroke treatment have led to an increased proportion of patients who can be discharged to their home from the stroke units ( Walsh et al., 2015). Stroke is now the second leading cause of death and a major cause of disability worldwide ( Katan and Luft, 2018). The global burden of stroke is increasing due to the world’s growing and aging population ( Béjot et al., 2016). This is something that health care professionals should be aware of when working with stroke patients. In line with previous studies, we found that female patients had higher odds of experiencing fatigue. ![]() ![]() As previous studies have shown that functional outcome, severity of stroke, and sex also correlate with fatigue after stroke, we controlled for these variables in our analysis. The correlation between cognitive impairment and fatigue that has been reported may be detectable no earlier than the subacute phase of stroke. We found that the cognitive function in an acute phase after stroke could not explain self-reported feeling of fatigue in a later stage. The data were analyzed using binary logistic regression. Data on self-reported feeling of fatigue were retrieved from Riksstroke’s 3-month follow-up form. Cognition was screened within 2 days after admission to the stroke unit. A total of 311 stroke patients admitted to a comprehensive stroke unit in Sweden between 20 were included in this longitudinal study. In the present study, we examined whether cognitive function screening using the Montreal Cognitive Assessment (MoCA) very early after stroke could explain fatigue 3 months after stroke. ![]() A correlation has been found between fatigue and cognitive impairment after stroke, but 2 months after stroke at the earliest. Early identification of risk factors for developing post-stroke fatigue is important for providing timely rehabilitation. Post-stroke fatigue has been reported as one of the most limiting symptoms after a stroke. Stroke is a major cause of disability and the second leading cause of death worldwide. 3Institute of Neuroscience and Physiology, Rehabilitation Medicine, University of Gothenburg, Gothenburg, Sweden.2Department of Occupational Therapy and Physiotherapy, Sahlgrenska University Hospital, Gothenburg, Sweden.1Department of Rehabilitation Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.Josefin Holmberg 1† Beatrice Jondell 1† Tamar Abzhandadze 2,3* Katharina S.
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